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2010 May;338(1-2):241-54

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Gastrointestinal Distress After Creatine Supplementation in Athletes: Are Side Effects Dose Dependent

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It was reported that GLP-1 (9-36) decreased the level of nuclear factor kappa-B (NF-B) in astrocytes after oxygen-glucose deprivation/reoxygenation (OGD/R) damage and inhibited neuronal apoptosis around the infarct area against CIR, the mechanism of which might be relying on the activation of the IGF-1 receptor rather than the GLP-1 receptor (91)

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instead, the multisystem pathologic processes that are associated with this condition have long been well established as drivers of its clinical presentation and outcomes

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