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Eating smaller meals, avoiding high-fat foods, staying hydrated, and following a tirzepatide-specific diet plan helps most patients manage these effects without needing to reduce their dose

Certain populations need to inject B12 in larger doses to maintain baseline health: Individuals with pernicious anemia are initially injected with 100 mcg daily for one week, followed by 100 mcg every other day for 3-4 weeks

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