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Interestingly, while BPC-157 promotes healing-associated angiogenesis, research also demonstrates it can inhibit tumor-promoting effects of VEGF signaling via the MAPK pathway in melanoma cell lines, suggesting context-dependent modulation of vascular growth that may preferentially support physiological tissue repair over pathological neovascularization

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[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Dolejov T., Sokol A., Bosk J., majs D., Konopsek I., Mikuov G., Fier R