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We mimicked condition of pressure overload in rats by TAC and observed the effect of semaglutide on LVH in TAC rats

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The semaglutide trial showed effect sizes in the medium to large range, he said, although he urged caution about the results since the trial was the first to look at this question in a controlled way. Semaglutide, sold by Novo Nordisk as Ozempic for type 2 diabetes and Wegovy for obesity, is part of a class of drugs known as GLP-1 receptor agonists, mimicking the hormone GLP-1 to reduce appetite, slow stomach emptying and regulate insulin