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In agreement with Burgess et al ., we observed a DET1 claw that embraces the Ube2e2 catalytic core on the backside -sheet, with the N-terminal Ube2e2 extension remaining flexible

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Conversely, administration of the colony stimulating factor-1 receptor (CSF-1R) inhibitor, PLX3397, in a mouse model of stroke eliminated microglia, resulting in increased infarct size, neuronal signaling dysregulation, and cell death, which was reversed markedly by microglial repopulation (Szalay et al., 2016)

Nerve growth factor enhances the therapeutic effect of mesenchymal stem cells on diabetic periodontitis