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It took about a year to assemble the funding for a one-year pilot program, identify a pharmacy to compound the semaglutide the active ingredient in some of the more costly, name-brand GLP-1s and find a doctor willing to prescribe the drug for off-label use to uninsured participants

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Researchers also found that 75% of them reached an A1C of 6.5%, a threshold associated with remission in diabetes

GLP-1 drugs (exenatide, liraglutide etc), as well as GIP/GLP-1 hybrid peptides (tirzepatide), are clinically approved for diabetes and/or obesity, with GLP-2 based drugs (teduglutide) approved for the treatment of short bowel syndrome