It acts as an extracellular proteinase inhibitor and is associated with cell differentiation processes, apoptosis and cancer [87, 88]
3 In B12 deficiency, methylmalonic acid (MMA) can accumulate, and it is thought that elevated MMA, alongside elevated homocysteine, contributes to damage of the myelin sheath (which protects nerve cells and speeds up nerve transmission), which can cause irreversible neurological problems
Alternatively, if the functional deficit in CFS patients leads to recruitment of abnormal ATP production pathways (63), carnitine supplementation might restore the use of normal reaction pathways, thus promoting metabolic flexibility
One enzyme, glutathione peroxidase, specifically requires glutathione to protect your cell membranes from oxidative damage.[1] 2