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Sample sizes were small (typically 6 to 12 animals per group)

In addition, berberine treatment was found to significantly increase IL-10 levels ( 2.2.2 Piperine Piperine alkaloids are naturally occurring alkaloids derived from the pepper plant that exhibit diverse pharmacological activities, such as antioxidant, anti-inflammatory, anticancer, and antibacterial effects ( 2.2.3 Resveratrol Resveratrol is a natural polyphenol found in many plants, including grape skins, red wine, blueberries and peanuts

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It has gained significant interest in research involving cellular energy balance, adipose metabolism, and metabolic optimization