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First, these low levels lead to increased production of cytokines and chemokines

It is now clear that GPR39 is not the receptor for obestatin and the original observation was likely the result of zinc in the preparations of obestatin

They also found that Gd-IgA1 stimulation caused a decrease in the activity of mesangial cells, accompanied by iron overload, lipid peroxide accumulation, mitochondrial morphological abnormalities and other biochemical and pathological phenotypes closely related to ferroptosis[161]

30 SunH.CaiH.XuC.ZhaiH.LuxF.XieY.et al (2022)