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Xiong R, Zhang L, Li S, Sun Y, Ding M, Wang Y, et al

Notably, we have revealed here that sustained intracellular GSH levels are essential for CD8 + T cell expansion, survival, and effector function and defined the complete dependence of such regulation on GPX4 expression and activity, through a metabolic signaling axis that ties the A2AR/PKA/E2F1 pathway to GSH metabolism and lipid peroxidation

Combination therapy: an upcoming paradigm to improve kidney and cardiovascular outcomes in chronic kidney disease

Next, to further verify the connection between CXCL10 and IL18R1 in fibrosis induction, we compared the effects of recombinant CXCL10 treatment (CXCL10 group) and CXCL10 plus IL18R1 antibody treatment (10+18ab) in in vitro-cultured ovaries