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The incidence of cholelithiasis and cholecystitis was higher in WEGOVY injection-treated pediatric patients aged 12 years and older than in WEGOVY injection-treated adults

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Semaglutide did not prolong QTc intervals at doses up to 1.5 mg at steady state

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The theoretical basis for any potential skin effects relates to GLP-1's broader metabolic actions rather than direct dermatological mechanisms

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Common side effects include: Nausea GI discomfort Fatigue during dose escalation Any serious adverse events in cardiovascular outcome trials were comparable to placebo

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