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Interestingly, in SURPASS-4, the overall cohort of tirzepatide users and those with 30 mg/g UACR experienced an acute dip in eGFR at 12 weeks, resembling the eGFR slope observed in trials with semaglutide and other nephroprotective drugs, such as RAAS blockers [50] and SGLT-2i [51]

Its important to follow any aftercare instructions provided by your healthcare provider and to monitor how you feel over time

These techniques enable visualization and quantification of NETs structures, though they vary in resolution, scalability, and specificity

Patients are encouraged to maintain a log of their doses, symptoms, and any changes in sleep patterns, which can help healthcare providers make informed adjustments to the treatment.