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For prevention of contrast-induced acute kidney injury, a meta-analysis found misleading beneficial associations that were lost when analysis was restricted to larger studies (52) , and mechanistic studies showed that oral NAC is poorly absorbed with no renoprotective effects (53)

Apart from the known side effects associated with pegvisomant, which are described above, potential adverse effects may be extrapolated from adult GH deficiency (AGHD)

Routes of Administration Subcutaneous injection (standard): Protocols describe injection in the abdomen, thigh, or upper arm, rotating sites between injections, using standard SC technique with a 29-31 gauge insulin syringe

10.1097/nen.0b013e31802c396b J