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The old designs also featured the words "Additive free", but those have been removed after claims by the Physicians for a Smoke-Free Canada organisation

For Empire Rolling marketing and distribution information: Contact Deborah Jennings, Marketing Director Phone: (703) 864-9177 Email: [email protected]

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Whereas most studies concerning tobacco smoke exposure have addressed the risk of carcinogenesis, our work has continuously focused on the impact of tobacco exposure, particularly that present at the time of cancer diagnosis and throughout treatment, on modulation of tumor biology, anti-tumor immunity and ultimately the effectiveness of chemoradiotherapy regimens [3, 4, 10, 11]