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For athletes and bodybuilders who are rehabilitating an injury IGF is vital to the proper production of connective tissue, and studies have shown that exogenous IGF administration may improve collagen formation and aid in the repair of cartilage and would greatly decrease recovery time as well as increase the strength of the recovered area

Systemic metabolic alterations and their relationship to neuropsychiatric symptomatology PAIS, including long COVID, as well as CFS and IMD, share the characteristic of systemic metabolic disturbances, which may be a sign of underlying multi-organ inflammation and exhaustion [31], and consequently may contribute to neuropsychiatric symptomatology, as many metabolites can cross the bloodbrain barrier (BBB) [30, 58] (e.g., short chain fatty acids (SCFAs) derived from the gut microbiota such as acetate [40], amino acids such as tryptophan [52] and also carnitine/acetylcarnitine can cross the BBB via transporters [59])

For readers exploring glutathione collagen support, the takeaway stays simple: protecting collagen depends heavily on managing oxidative stress aging at the cellular level