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Integrins comprise a family of over 24 noncovalent, transmembrane heterodimers and have different ligand-binding specificities ( 2 O 2 activates p38 MAPK-3 feedback regulation, which consequently upregulates the expression of the 3 chain, even v3 ( Chondroitin sulfate (CS) is an important polysaccharide belonging to the family of glycosaminoglycans (GAGs) and is ubiquitously expressed on the cell surface

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Moreover, the GSK3-Nrf2 signaling pathway could obstruct ferroptosis via its antioxidant potential (Huang et al., 2022a)

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