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[DOI] [PubMed] [Google Scholar] 81.Weisler RH, Hirschfeld R, Cutler AJ, Gazda T, Ketter TA, Keck PE, et al

The aberrant downregulation of SMO-SHH signals contributes to the proteolytic cleavage of GLI (glioma-associated homolog) into GLI3 (repressor), which increases oxidative stress, neuronal excitotoxicity, neuroinflammation, and apoptosis by suppressing target gene expression

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