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After 10 years of treatment, the incidence of MALE was significantly lower in the GLP-1RAs group than in the non-GLP-1RAs group (Celsa et al., 2025)

This research deepens our understanding of NRF2s role in cellular homeostasis and lays the foundation for the development of NRF2-targeted therapies

From Figure 5D, the MDA level in the control group of cells was low at 2.49 0.25 nmol/mg pro, and the MDA level in the damaged group was significantly higher at 11.16 0.088 nmol/mg pro as compared to the control group

Considering that aneuploidy is an important contributor to nuclear maturation defects in oocytes, we evaluated spindle morphology, chromosome alignment, and chromosomal integrity in oocytes from each group