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Seek urgent medical attention (contact your GP immediately or attend A&E) if you experience: Severe, persistent abdominal pain (possible pancreatitis) Signs of allergic reaction: rash, swelling of face or throat, difficulty breathing Chest pain, severe palpitations, or irregular heartbeat Severe dehydration from vomiting or diarrhoea Symptoms of hypoglycaemia if you also have diabetes and take insulin or sulfonylureas: confusion, sweating, tremor, rapid heartbeat Regular monitoring schedule : Patients taking both medications should have thyroid function tests every 68 weeks after significant weight loss or dose changes, then annually once stable

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Additionally, the trial design may lead to higher screening failure rates in non-White populations and thus trial populations may not be representative

In fact, one in three American adults has at least one of these major risk factors, which explains why almost 800,000 people in the U.S