Circulation 120 , 20122024 (2009)
Emerging research highlights the importance of optimal intake of vitamin K and its critical role in maintaining bone and cardiovascular health
Interventions Participants consumed one sachet of either i) L-Carnitine-combination (1500 mg given as 2200 mg Carnipure tartrate (Lonza, Switzerland), 2000 mg L-leucine, 3000 mg creatine monohydrate, and 0.01 mg (400 IU) of vitamin-D3), ii) L-Carnitine (1500 mg given as 2200 mg Carnipure tartrate (Lonza, Switzerland)), or iii) appearance- and taste-matched placebo each day, in the morning with breakfast
Formula Analysis We examined each products ingredient list against published NAD+ research to verify: Precursor dosing aligns with amounts shown effective in clinical trials (250-2,000mg for NR, 300-1,200mg for NMN) Supporting ingredients have evidence for enhancing or sustaining NAD+ production No proprietary blends that hide actual ingredient amounts Absence of unnecessary fillers or underdosed window dressing ingredients We gave preference to formulas addressing multiple aspects of cellular energy metabolism rather than relying on a single precursor alone