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That is a statistically significant difference, but the magnitude of weight loss is modest by any standard

Patients in STEP 1 were desirous of weight loss as a reason for study participation and received structured lifestyle intervention (which included a 500 kcal per day diet with 150 min per week of physical activity)

On August 13, 2025, CMS released updated CMS Medicare Part B vaccine payment allowance limits for the 2025 to 2026 influenza season, effective August 1, 2025, through July 31, 2026

We also note that this accommodates potential for collective improvementif hospitals with at least three Safety of Care measures improve in performance relative to those with one or two, then fewer than 25 percent of those with at least three measures would find themselves in that lowest overall quartile