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Andersson, Emmanuel Shapira, Biochemical and clinical response to hydroxocobalamin versus cyanocobalamin treatment in patients with methylmalonic acidemia and homocystinuria (cblC), The Journal of Pediatrics, Volume 132, Issue 1, January 1998, Pages 121-124, ISSN 0022-3476, Okuda K, Yashima K, Kitazaki T, Takara I

Key quantitative findings included dose-dependent increases in CXXC5 expression following PGD2 treatment, corresponding decreases in beta-catenin and PCNA (a proliferation marker), restoration of Wnt signaling and cellular proliferation with PTD-DBM treatment, and complete resistance to PGD2-induced hair loss in CXXC5 knockout mice

In research models, cagrilintide is designed to activate receptors linked to satiety, food intake, gastric emptying, and metabolic control