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This study demonstrated that ERT not only ameliorated structural deformities but also reduced oxidative stress and increased the gene expression of kidney cells in Fabry kidney organoids, which means that Fabry kidney organoids are useful tools for investigating the efficacy of ERT and will contribute to the development of new forms of ERT

Importantly, this study cannot rule out other mechanisms whereby naltrexone may modulate ketamines acute antidepressant response through alternative direct and/or indirect actions at the mu opioid receptors 41

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But these medications contain different active drugs