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These are the real villains behind smoking-related diseases

Evaluation of electronic cigarette use (vaping) topography and estimation of liquid consumption: implications for research protocol standards definition and for public health authorities regulation

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People with an addiction will feel a compelling need to engage in some behavior, such as using a drug (which can be alcohol, the nicotine in tobacco, a prescription drug or an illegal chemical such as cocaine or heroin) even when the user knows that doing so risks severe health or legal consequences